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Image Search Results
Journal: Scientific reports
Article Title: Biparatopic anti-PCSK9 antibody enhances the LDL-uptake in HepG2 cells.
doi: 10.1038/s41598-024-66290-9
Figure Lengend Snippet: Figure 2. The epitope binning assay- comparison between VHH-H2/D8/B11 and Repatha by SPR. The epitope binning assay consists of four steps: chip capturing; binding PCSK9 to saturation; adding secondary antibody; Protein A chip regeneration. (A) It shows the binding-epitope differences between VHH-H2/D8/B11 and Repatha by SPR. (B) It shows the binding-epitope differences between VHH-H2/D8 and VHH-B11 by SPR. The horizontal axis represents the timeline. The vertical axis represents the relative response unit.
Article Snippet: Firstly, evolocumab (also known as the Repatha, CAS# 1256937-27-5, Amgen, USA), diluted to 2 μg/mL, was captured on the flow cell 2 (FC2) of the
Techniques: Comparison, Binding Assay